European Registry of Next Generation Imaging in Advanced Prostate Cancer

Status: Recruiting
Location: See all (24) locations...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

The RING study is a European registry collecting real-world data on advanced prostate cancer (APC) imaging. It aims to evaluate the role of next-generation imaging (NGI), such as PET/CT and whole-body MRI, in detecting and monitoring the disease compared to conventional imaging. Men aged 18 or older with histologically confirmed prostate cancer are eligible to participate in the study if they require imaging to assess potential metastases, either at diagnosis or after relapse and sign a consent form. Patients will receive standard care with no experimental treatments. Imaging and treatment decisions will follow routine clinical practice. Data will be collected from medical records and analysed for research. This study will help doctors understand when NGI should be used, how it affects treatment decisions, and its impact on patient outcomes.

Eligibility
Participation Requirements
Sex: Male
Minimum Age: 18
Healthy Volunteers: f
View:

• Adult male patients (≥18 years with no upper age limit).

• Histologically proven prostate cancer.

• Patients who require imaging exploration (conventional, Next-Generation Imaging (NGI), or their combination) at high risk for harbouring metastatic deposits at the hormone-sensitive stage, either at the diagnostic workout of a naïve patient or at biochemical relapse/progression after local treatment.

• Patients who authorize their participation in the study by signing a written informed consent form (ICF).

Locations
Other Locations
Belgium
Universitair Ziekenhuis Leuven
NOT_YET_RECRUITING
Leuven
France
Hospital Center University De Lille
NOT_YET_RECRUITING
Lille
Hospices Civils de Lyon
NOT_YET_RECRUITING
Lyon
University Hospitals Pitié Salpêtrière
NOT_YET_RECRUITING
Paris
Germany
Bonn University Hospital
NOT_YET_RECRUITING
Bonn
Martini Klinik
NOT_YET_RECRUITING
Hamburg
München LMU L MU-University Clinic
NOT_YET_RECRUITING
Munich
Urologische Klinik München - Planegg
NOT_YET_RECRUITING
Planegg
Universitätsklinik Tübingen
NOT_YET_RECRUITING
Tübingen
Italy
IRCCS Universit of Bologna
NOT_YET_RECRUITING
Bologna
Azienda Ospedaliero-Universitaria Careggi
RECRUITING
Florence
Azienda Ospedaliero-Universitaria Careggi
NOT_YET_RECRUITING
Florence
IRCCS Ospedale San Raffaele
NOT_YET_RECRUITING
Milan
Netherlands
ERASMUS MC & Franciscus Hospital
NOT_YET_RECRUITING
Rotterdam
Poland
Uniwersytet Jagielloński Collegium Medicum
NOT_YET_RECRUITING
Krakow
Spain
Fundació Puigvert
RECRUITING
Barcelona
Hospital de la Santa Creu i Sant Pau
RECRUITING
Barcelona
Hospital Universitario Reina Sofia
NOT_YET_RECRUITING
Córdoba
Hospital Universitario La Paz
NOT_YET_RECRUITING
Madrid
Hospital Universitario Ramón y Cajal
NOT_YET_RECRUITING
Madrid
Hospital Universitario de Canarias
RECRUITING
San Cristóbal De La Laguna
Hospital Universitario Marqués de Valdecilla
NOT_YET_RECRUITING
Santander
Hospital Clínico Universitario de Santiago
NOT_YET_RECRUITING
Santiago De Compostela
Sweden
Skånes universitetssjukhus Malmö
NOT_YET_RECRUITING
Malmo
Contact Information
Primary
Francesco Sanguedolce, MD, PhD
fsanguedol@fundacio-puigvert.es
+34934169100
Backup
Daria Chernysheva, MD, PhD
daria.chern@gmail.com
+34672034192
Time Frame
Start Date: 2024-09-17
Estimated Completion Date: 2026-12-23
Participants
Target number of participants: 600
Treatments
New generation imaging
Patients with prostate cancer at high risk for harbouring metastatic deposits at the hormone-sensitive stage, who require imaging exploration either at the diagnostic workup of a naïve patient or at biochemical relapse/progression after local treatment with the use of next generation imaging ( whole-body MRI and PET/CT with new tracers (F/Ga-PSMA, 18F-fluciclovine)
Conventional imaging
Patients with prostate cancer at high risk for harbouring metastatic deposits at the hormone-sensitive stage, who require imaging exploration either at the diagnostic workup of a naïve patient or at biochemical relapse/progression after local treatment with the use of conventional imaging ( CT and bone scan)
Conventional imaging and New generation imaging
Patients with prostate cancer at high risk for harbouring metastatic deposits at the hormone-sensitive stage, who require imaging exploration either at the diagnostic workup of a naïve patient or at biochemical relapse/progression after local treatment with the use of conventional imaging ( CT and bone scan) AND next generation imaging
Related Therapeutic Areas
Sponsors
Collaborators: GUARD Consortium (Genitourinary Alliance for Research and Development), Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau, European Association of Urology Research Foundation, Johnson & Johnson, European Association of Urology - Section of Urological Imaging
Leads: Fundacio Puigvert

This content was sourced from clinicaltrials.gov